I never thought about it before but I use upstream and downstream without much though. For my personal devices and containers I use Fedora but when it comes to servers and VMs I use Debian for its stable nature.
I also run Linux mint in my homelab with pcie pass though so it functions like a normal desktop.
I’ll go against the grain a little bit and say it’s a little weird. There’s nothing wrong with liking multiple distros, but a lot of people either stick with RPM-based (Red Hat, Fedora, CentOS, Rocky, OpenSUSE, Mageia) or Debian-based (Debian, Ubuntu, Mint, Pop!, Elementary). Then you have weirdos that like Gentoo, where nearly every package you install has to be compiled on the system. Or Arch, where the “installer” throws you in a terminal, and damn near everything has to be done manually to get your system up and running. And updates are “rolling release”, and if you try to update just one package without updating the rest of your system things can easily break.
I am mostly a fan of Debian-based distros myself. But I’ll use CentOS on a VM if I’m trying to self-host anything that recommends it.