In the long run, using mice to test human medicines will result in selection pressure for humans whose physiology more and more closely resembles mice.
Actually it’s used in everything, it’s available, it’s well studied, it’s cheap, and most importantly it grows fast in a lab, so it’s easy to work with…
I wish I was joking, but lots of in vitro human research is done on the poor women’s cancer cells when the research has nothing to do with cancer, it’s quite the confounder
Mice, notorious for having evolved to suit unclean conditions and being able to survive as carriers of disease and parasites will definitely have a different set of evolved resistances and immunities to us. It’s pretty ludacris science believes them to be a good point of comparison.
It’s just an early testing phase, more of an “ok, this drug kind of did what we want in mice, and the mice didn’t explode. It’s time to move to the next stage of testing on something more human analogue, like a pig.”
In the long run, using mice to test human medicines will result in selection pressure for humans whose physiology more and more closely resembles mice.
No! We will be crab! Everything becomes crab!
they use a lot of other things… including living human cancer cells in a petri dish
I believe the vast majority of cultivated human cells are cancerous cells anyway.
https://en.wikipedia.org/wiki/Henrietta_Lacks
when researching cancer drugs, yeah
Actually it’s used in everything, it’s available, it’s well studied, it’s cheap, and most importantly it grows fast in a lab, so it’s easy to work with…
I wish I was joking, but lots of in vitro human research is done on the poor women’s cancer cells when the research has nothing to do with cancer, it’s quite the confounder
they use stem cells a lot for that sort of thing too
So we will become cancer
Maybe the real cancer is the friends we made along the way
The reality is that even if there was a magic bullet for cancer, all cancer, it would only extend lives a few years.
How does that work?
well no, they kill cancer in petri dishes
It was a joke about selection pressure.
i love this idea let’s become mice
they are widely known to be the smartest creatures on earth, followed by dolphins, and then us
No, we will become monke
Mice live 9 months in the wild, and have a resting heart rate of 500-700 bpm. That’s a lot of cardio.
That’s not how evolution works though
Assuming that
human phenotypic traits that correlate more closely with mouse traits have more-predictable outcomes with mouse-tested medicine, and
more-predictable medical outcomes correlate with higher survival and reproductive rates,
can’t you plug that straight into the Price equation?
Mice, notorious for having evolved to suit unclean conditions and being able to survive as carriers of disease and parasites will definitely have a different set of evolved resistances and immunities to us. It’s pretty ludacris science believes them to be a good point of comparison.
It’s just an early testing phase, more of an “ok, this drug kind of did what we want in mice, and the mice didn’t explode. It’s time to move to the next stage of testing on something more human analogue, like a pig.”
You know lab mice aren’t just grabbed out of the sewers, right?
Not when the sewer mice have turtles to protect them