She can still be a horrible person and still dislike Donald.

She stays away from him a lot, when he tried to hold her hand she actively swatted it away.

It may simply be that she sees him as ugly, old, and gross, even if she has no particular objections to him morally or ethically. He was a viable way to a luxurious life, but particularly this first lady stuff imposes on her and is annoying, even as she mostly shrugs it off.